Alzheimer’s disease may be ‘at work’ years ahead of actual symptoms, claim IU researchers The best-known genetic variant associated with Alzheimer's disease may be ‘at the job’ promoting deposits of plaque in the brain long before any symptoms of the disease can be measured on checks, according to a national research study led by Indiana University School of Medicine investigators alternative . In a study paper released in the journal Alzheimer's and Dementia, the researchers provide additional evidence for focusing study, and eventually treatment, on people at risk of Alzheimer's long before the disease is diagnosed.
The study was published in the American Medical Association’s Archives of Neurology. Geert De Meyer of Ghent University in Belgium and co-workers in the Alzheimer’s Disease Neuroimaging Initiative analyzed data from 114 old adults who were cognitively normal, 200 who had mild cognitive impairment and 102 who experienced Alzheimer’s disease for the study. They found a specific biomarker signature that’s present in a lot more than 90 % of the Alzheimer’s group, 72 % of these with slight cognitive impairment and 36 % of these who were cognitively regular. They checked the data on two other smaller groups.