New technology used to create the first map of structural variation in the human genome Constructis beyond the simple power of one-letter characters in the human genome sequence is a complex, higher-level code. Defined as large deletions and duplications of DNA segments – To decrypt this level of architecture, scientists have realize powerful new experimental and algorithmic methods of copy number variants develops. These technologies – reported in the journal Genome Research – were used to create the first comprehensive map of CNVs in the human genome, in Nature in Nature reviews . A related article appears in Nature Genetics.
The microarray technology, scientists can for CNVs across the genome scan in a single experiment. While this is a cost-effective means of generating large amounts of data, scientists have struggled to accurately determine CNV copy number and to precisely define the boundaries of CNVs in the genome. Two papers published in Genome Research present groundbreaking approaches to address these problems.
Hospital in almost a third the cases of sudden cardiac arrest do not recommended into patients defibrillate time to 15 percent delay and increase their risk for brain damage and death, for a study published Thursday the New England on The New York Times. The study, led by Paul Chan of St. Luke’s Mid America Heart Institute, examines the research the medical records of 6,789 patients in 369 hospital in a national register of heart failure by American Heart Association .
According to this study, accumulated based on data between 2000 and 2005, will receive 70 percent of participating defibrillation to their hearts within the recommended time from under two minutes their their cardiac arrest, with to a survival rate 39 percent. Via 17 percent of participants received defibrillate between three and five minutes of their cardiac arrest, a survival rate 28 percent, the study found. Operators who were defibrillate for more than five minutes after her heart failure , had had a survival rate of 15 percent after the trial (Winstein, the Wall Street Journal.