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The researchers used the bacterium Staphylococcus aureus as the model for his or her experiment, since it is one of the significant reasons of hospital-acquired illness and also plays an essential role in the lung attacks which are normal in the genetic disorder cystic fibrosis. The small clarithromycin nanoparticles , could actually access the bacteria located either in biofilms or inside individual lung cells. Neither of the locations is definitely conducive to effective drug delivery through traditional routes, says Dr Carvalho-Wodarz, so we were very happy to see that not only did the use of CLARI-NPs allow the uptake of the antibiotic by the lung cells, but also that there have been no toxic effects on all of the cell types on which we tested.