Caspase inhibition may prevent brain inflammation in neurological diseases Neurodegenerative diseases like Alzheimer’s and Parkinson’s are partly due to brain inflammation. Experts at Karolinska Institutet today demonstrate in a paper published in Nature a well-known family of enzymes can prevent the inflammation and thus constitute a potential target for drugs. Research suggests that microglial cells – the nerve system’s primary immune cells – play a critical part in neurodegenerative diseases, such as for example Alzheimer’s and Parkinson’s. The over-activation of these cells in the brain can cause inflammation, leading to neuronal death. Scientists at Karolinska Institutet and Seville University, working in collaboration with co-workers at Lund University, have finally found a real way to prevent the activation of the microglia and therefore the irritation they cause.Related StoriesCornell biomedical engineers develop 'very natural killer cells' to destroy tumor cells in lymph nodesNew RNA test of blood platelets can be used to identify location of cancerMeat-rich diet plan may increase kidney cancer riskAlthough the results support a role for vitamin D in the etiology of colorectal cancer tumor, the authors caution that hardly any is known about the association of supplement D with various other cancers and that the long term health effects of high circulating vitamin D concentrations, potentially obtained by taking products and/or widespread fortification of some food products, have not really been well studied.